There are some women who have a higher risk of developing ovarian or uterine cancer. The family history, genetic associations and other cancers can increase the risks. There is role of prophylactic interventions to reduce the risk of cancer such as prophylactic oophorectomy in high-risk groups.
Postmenopausal bleeding and irregular periods after the age of 45 poses a risk of uterine cancer. Early referral, pelvic ultrasound scan and uterine biopsy is a key to early detection of uterine cancer.